Nidus is a grotesquely beautiful Warframe with an organic, infested aesthetic. Its body features asymmetrical, tumor-like growths and exposed tendrils that pulse with a sickly glow. The frame's armor is a mix of smooth, carapace-like plates and rough, fleshy textures, with a color palette that leans towards deep reds, purples, and blacks, accentuated by bioluminescent highlights. Distinctive design elements include a helmet with a single, large eye-like visor and a mouth-like slit, giving it a sinister appearance. The Warframe's overall form is hunched and predatory, with elongated limbs and a spine that protrudes through its back, emphasizing its connection to the Infestation.